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Changes for version 0.80 - 2007-03-22

  • GO::OntologyProvider::OboParser
  • New module, contributed by Shuai Weng of SGD. This allows you to use the .obo files instead of the .ontology files. The .ontology files have been deprecated for a while, and are much bigger than the .obo version, as they contain redundant information. The ontology parsing module still ships, but will be deprecated in future versions. The test suite for the ontology parser no longer ships with the distribution, though I still test it locally.
  • Note, the API for the OboParser is slightly different, in that you have to provide the aspect of the ontology that you want (P, C or F), which was not the case when parsing the .ontology files.
  • All the example code in the examples/ directory has been updated to work with the obo parser.
  • GO::TermFinder
  • Updated to deal with the loss of the 'unknown' nodes in the ontology. With the removal of those nodes, direct annotation to the aspect node, such as biological_process, is meaningful. Thus, it now tests for significance for genes annotated directly to the aspect nodes, ignoring indirect annotations to those nodes.
  • Added an additional check, such that if you provide a background population, but none of the genes in your list of interest are in that population, it dies with a useful error message (as opposed to the previously useless one).
  • Corrected a bug in the Bonferroni correction, where it was too conservative - not sure what I was thinking.
  • GO::TermFinderReport::Text
  • Can now print out the results in tabular form, instead of the usual text version, to help with automated analyses. Thanks to Noah Zimmerman for the code changes.
  • Code Quality
  • I have started to use Perl::Critic locally, and all the code at least passes level 5. Future revisions will pass harsher review (with some rules commented out!).
  • Compilation
  • The native/Makefile.PL has been modified to hopefully make it compile correctly under Cygwin - thanks to Noah Zimmerman for help with testing.

Modules

abstract base class defining interface for how Annotation information should be provided
parses a gene annotation file
provides information about a node in the Gene Ontology
abstract base class providing API for the provision on Gene Ontology information
Provides API for retrieving data from Gene Ontology obo file.
Provides API for retrieving data from Gene Ontology files
identify GO nodes that annotate a group of genes with a significant p-value
prints an html table of the results of GO::TermFinder
prints results of GO::TermFinder as a text report
simply utility module for dealing with file parsing
provides some general utilities for clients of other GO classes
Creates a gif or png image for visualizing the GO DAG
a helper class for GO::View to deal with the image

Provides

in lib/GO/TermFinder/Native.pm
in lib/GO/TermFinder/Native.pm
in lib/GO/TermFinder/Native.pm